• Oxybutynin MR (Lyrinel XL) 

    It is not acceptable for short-term use prior to bladder surgery. Only the sustained-release formulation is permitted.

    Tolterodine MR (Detrusitol XL)

    Solifenacin (Vesicare)

    Darifenacin (Emselex)

    Trospium IR and MR (Regurin)

    Side-effects to enquire about are mainly anti-cholinergic such as dry mouth, blurred vision and drowsiness. If these do not occur in the first few months they are extremely unlikely to occur later.

    Class 1

    Unfit for a minimum of four weeks or until a stable dose is achieved with adequate symptom control.
    OML for at least four months.

    If the dose of drug remains stable with satisfactory symptom control and no reported side-effects, then unrestricted certification can be considered at four months. Any change in dosage should entail a grounding period of four weeks followed by reassessment. Pilots should be advised to keep themselves hydrated before and during flights.

    Class 2

    Unfit for a minimum of four weeks or until a stable dose to achieve with adequate symptom control. If the dose of drug remains stable with satisfactory symptom control and no reported side-effects, then unrestricted certification can be considered at four weeks. Any change in dosage should entail a grounding period of four weeks, followed by reassessment.