Oxybutynin MR (Lyrinel XL)
It is not acceptable for short-term use prior to bladder
surgery. Only the sustained-release formulation is permitted.
Tolterodine MR (Detrusitol XL)
Solifenacin (Vesicare)
Darifenacin (Emselex)
Trospium IR and MR (Regurin)
Side-effects to enquire about are mainly anti-cholinergic
such as dry mouth, blurred vision and drowsiness. If these do not occur in the
first few months they are extremely unlikely to occur later.
Class 1
Unfit for a minimum of four weeks or until a stable dose is
achieved with adequate symptom control.
OML for at least four months.
If the dose of drug remains stable with satisfactory symptom
control and no reported side-effects, then unrestricted certification can be
considered at four months. Any change in dosage should entail a grounding
period of four weeks followed by reassessment. Pilots should be advised to keep
themselves hydrated before and during flights.
Class 2
Unfit for a minimum of four weeks or until a stable dose to
achieve with adequate symptom control. If the dose of drug remains stable with
satisfactory symptom control and no reported side-effects, then unrestricted
certification can be considered at four weeks. Any change in dosage should
entail a grounding period of four weeks, followed by reassessment.